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Study Finds Benefits For Autism Patients Following Use Of CBD-Rich Cannabis

Cannabidiol (CBD) is arguably the most popular cannabinoid on earth right now, at least among lawmakers. Whereas elected officials are unfortunately still reluctant to reform cannabis laws pertaining to THC in many areas, more and more of them are opening up to CBD reform.

The spread of CBD reform has been paralleled by a rise in CBD research, which is a great thing for patients everywhere. A recent study in Israel found that the use of CBD-rich cannabis may provide benefits to autism patients. Below is more information about it via a news release from NORML:

Tel Aviv, Israel: The administration of CBD-rich cannabis is associated with clinical improvements in adolescents with autism spectrum disorder (ASD), according to data published in the journal Translational Psychiatry.

Israeli researchers evaluated the efficacy of cannabis treatment in a cohort of 82 young people (ages 5 to 25) with ASD. Subjects in the trial consumed whole-plant cannabis extracts (oils with a CBD:THC ratio of 20 to 1) adjunctively over a period of six months. Investigators used a variety of standardized clinical assessments to evaluate patients’ symptoms prior to and immediately following treatment.

They reported, “Our results revealed significant improvements in [the] overall … scores of the ASD participants who completed the 6-month treatment protocol with CBD-rich cannabis. Overall changes were mostly driven by improvements in social communication skills.

“[T]hese findings suggest that treatment with CBD-rich medicinal cannabis can lead to significant improvements in social communication skills of some ASD individuals, particularly those with more severe initial symptoms,” authors concluded. “These positive findings motivate further double-blind placebo-controlled studies for determining the efficacy of treatment with specific cannabis strains and/or synthetic cannabinoids.

The researchers’ findings are consistent with those of numerous other studies demonstrating that the use of either CBD-dominant cannabis or oral extracts is associated with symptom mitigation in adolescents with ASD.

Full text of the study, “Children and adolescents with ASD treated with CBD-rich cannabis exhibit significant improvements, particularly in social symptoms: An open label study,” appears in Translational Psychiatry. Additional information on cannabis and ASD is available from NORML.

Why Are Canadian Doctors Still So Unfamiliar With Medical Cannabis?

Despite what some governments around the world may claim, cannabis does indeed possess tremendous medical value, as proven by a growing number of peer reviewed studies and personal testimonies from suffering patients that have successfully treated their condition(s) with cannabis.

Fortunately, more and more cannabis laws are being reformed around the world which is boosting safe access to medical cannabis. For instance, Canada has had a medical cannabis program for several decades now, and is the only G-7 nation to have a nationwide adult-use law on the books.

For some reason, doctors and medical professionals in Canada are still lagging behind when it comes to knowledge of medical cannabis and related topics. Below is more information about it via a news release from NORML:

Montreal, Canada: Despite the federal government having legalized patients’ access to marijuana two decades ago, most Canadian health care providers acknowledge that they possess little knowledge about medical cannabis and almost none report having received any training about it while in medical school.

Survey data published in the journal BMC Complementary Medicine and Therapies reported that 56 percent of respondents felt either “uncomfortable or ambivalent regarding their knowledge of medical cannabis,” and that only six percent of medical professionals received any formal training about it while attending medical school. (By contrast, 60 percent of respondents said that they had   attended either a workshop or a conference on the topic.) Fewer than one-in-three (27 percent) acknowledged being familiar with the regulations surrounding patients’ access to medical cannabis products.

The results are consistent with numerous other surveys from the United States and abroad finding that health professionals seldom receive any formal training about cannabis and that most lack sufficient understanding of the subject.

Authors concluded: “The majority of HCPs [health care practitioners] received little, if any, formal training in cannabinoid-based medicine in medical school or residency, … and nearly one-third were unfamiliar with the requirements for obtaining CMP [cannabis for medical purposes] in Canada. Respondents endorsed discomfort with their knowledge of MC [medical cannabis.] …. These findings suggest that medical training programs must reassess their curricula to enable HCPs to gain the knowledge and comfort required to meet the evolving needs of patients.”

Full text of the study, “Healthcare practitioner perceptions on barriers impacting cannabis prescribing practices,” appears in BMC Complementary Medicine and Therapies. Additional information is available in NORML’s fact sheet, ‘Health Clinicians Attitudes Toward Cannabis.’

Canadian Case Study Finds Favorable Results For CBD Oil And Autism

It is estimated that over 75 million people worldwide have been diagnosed with autism, with countless other people going undiagnosed for one reason or another. The first diagnosis of autism occurred roughly 75 years ago, and the definition of what constitutes autism has evolved since that time.

Currently, autism is defined by Autism Speaks as, “a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.”

The most common types of developmental therapy for people with autism include speech and language therapy, which has been found to improve the person’s understanding and use of speech and language, particularly in social interactions.

A recent study in Canada found that CBD oil may be an effective treatment for those diagnosed with autism. Below is more information about it via a news release from NORML:

Toronto, Canada: The administration of plant-derived CBD oil is safe and effective in the treatment of autism-related symptoms and it ought to be considered as a viable treatment option for patients with the disorder, according to the findings of a case study published in the journal Cureus.

A team of Canadian investigators assessed the long-term use of CBD oil containing 20 mg of CBD and less than one mg of THC in a non-verbal pediatric patient with autism spectrum disorder. Prior to initiating CBD treatment, the patient exhibited behavioral symptoms with outbursts of anger and physical aggression (e.g., punching, kicking, biting, head-butting, and scratching).

Following twice-daily CBD treatment, the patient “experienced a reduction in negative behaviors, including violent outbursts, self-injurious behaviors, and sleep disruptions. There was an improvement in social interactions, concentration, and emotional stability.”

Investigators concluded: “In the case study presented, the child patient has shown behavioral and cognitive improvements with no side effects reported. … With the increasing clinical studies on the use of cannabidiol in treating patients with mood disorders, anxiety, chronic pain conditions, and other behavioral problems, it should be considered as a treatment option in managing symptoms related to autism.”

The findings are consistent with numerous other studies demonstrating that the use of either CBD-dominant cannabis or oral extracts is associated with symptom mitigation in children with ASD.

Full text of the study, “Cannabidiol in treatment of autism spectrum disorder: A case study,” appears in Cureus. Additional information on cannabis and ASD is available from NORML.

THC Provides Symptomatic Relief To Patients With Tourette Syndrome

As many as one percent of people worldwide suffer from Tourette Syndrome to some degree, although many cases go undiagnosed. Tourette Syndrome is a nervous system disorder that involves the patient making repetitive movements and/or unwanted sounds.

Most cases of Tourette’s Syndrome start when the sufferer is a child, with some cases getting worse as the patient gets older. Typical treatments for Tourette Syndrome includes pharmaceutical medications and/or psychological therapies.

Cannabis is another form of treatment for Tourette Syndrome, albeit an emerging form of treatment that is not as common. A recent study in Canada found cannabis to be effective in some cases. Below is more information about it via a news release from NORML:

Toronto, Canada: Vaporized cannabis containing ten percent THC provides symptomatic relief to patients with Tourette Syndrome (TS), according to placebo-controlled data published in the journal Cannabis and Cannabinoid Research.

Canadian researchers assessed the short-term effects of vaporized cannabis of varying potencies versus placebo in nine patients with TS.

They reported that subjects exhibited and perceived modest improvements following the administration of THC-dominant cannabis, but that they failed to demonstrate similar improvements following the use of either lower THC cannabis and/or high-CBD cannabis. Researchers acknowledged, “[G]iven the small sample size, … it is difficult to draw definitive conclusions about the benefits of THC.”

Prior studies assessing the long-term use of oral THC have documented a reduction in tics in TS patients. The findings of a 2019 study concluded, “Medical cannabis seems to hold promise in the treatment of GTS [Gilles de la Tourette syndrome] as it demonstrated high subjective satisfaction by most patients however not without side effects and should be further investigated as a treatment option for this syndrome.”

Full text of the study, “A double-blind, randomized, controlled crossover trial of cannabis in adults with Tourette Syndrome,” appears in Cannabis and Cannabinoid Research. Additional information on cannabis and TS is available from NORML.

UK Study Finds Cannabis Consumption Is Not Linked To Changes In Motivation

Historically, cannabis consumers have been portrayed by cannabis opponents as lazy ‘do nothings’ that sit on couches all day eating potato chips. Those stereotypes have also been perpetuated in mainstream media.

Unfortunately for cannabis opponents, there are numerous examples of people in peak physical condition that consume cannabis every single day, as demonstrated by the growing number of professional athletes that are coming out of the cannabis closet.

To be fair, there are certainly cannabis consumers that lack motivation, however, it’s not because of the cannabis. Some people are just lazy. That is reflected in the results of a recent study out of the United Kingdom. Below is more information about it via a news release from NORML:

London, United Kingdom: Neither adults nor young people who consume cannabis exhibit symptoms of so-called ‘a-motivational syndrome,’ according to case control data published in The International Journal of Neuropsychopharmacology.

British researchers assessed apathy, anhedonia (an inability to feel pleasure), and effort-based decision making in a cohort of late-adolescent and young adult cannabis consumers. Their performance was compared to that of age-matched controls (non-cannabis consumers).

Researchers identified no significant differences between the two groups.

“Cannabis use has historically been linked with a-motivation, which is reflected in prevalent, pejorative ‘lazy stoner’ stereotypes. In this study, we counter this cliché by showing that a relatively large group of adult and adolescent cannabis users and controls did not differ on several measures of reward and motivation,” they concluded. “Specifically, people who used cannabis on average four days per week did not report greater apathy or anhedonia, reduced willingness to expend effort for reward, or reduced reward wanting or liking compared to people who did not use cannabis. … Our results add to the growing body of evidence suggesting that non-acute cannabis use is not linked with amotivation, which may help to reduce stigma experienced by people who use cannabis.”

The investigators’ findings are consistent with those of other recent studies refuting long standing claims that those with a history of marijuana use typically lack motivation.

Full text of the study, “Anhedonia, apathy, pleasure, and effort-based decision-making in adult and adolescent cannabis users and controls,” appears in The International Journal of Neuropsychopharmacology.

Attend CanEx Jamaica Business Conference And Expo September 15-17th, 2022

The fifth installment of CanEx Business Conference and Expo is taking place in Montego Bay, Jamaica from September 15-17, 2022. The CanEx Jamaica Business Conference and Expo is an annual business-to-business (B2B) event that brings together global cannabis industry experts.

The conference will provide insight into the global direction of the industry and will feature a mix of high-level discourse and practical opportunities led by global experts with real-life applications in the cannabis industry. Presenters will discuss opportunities for investment, medical advances and uses, and the current legal landscape of the emerging global cannabis industry.

Event attendees can look forward to numerous networking events that will host robust panel discussions on such topics as:

  • Cannabis for All: Ensuring Equitable Cannabis Regulation
  • Psychedelics: Transforming Mental Health Options
  • Developing A Dynamic Cannabis Industry in Jamaica
  • Understanding Today’s Cannabis Investment Climate
  • Reggae Music, Cannabis Culture, and Embracing the NFT Opportunity

Leading up to the event, organizers interviewed the conference’s four keynote speakers – Founder and CEO of Simply Pure Wanda James, President and CEO of the Marijuana Policy Project Toi Hutchinson, renowned cell biologist Dr. Annabelle Manalo-Morgan, and President and CEO of Bhang Inc. Jamie L Pearson. Below is what the speakers had to say about CanEx Jamaica:

“I’ve always wanted to contribute to cannabis research in the Caribbean. My husband Gramps Morgan and the Morgan Heritage family are from the beautiful hills of St. Thomas Jamaica which has the ability to grow incredible organic cannabis, so Jamaica is very dear to me. I have always heard about Canex bringing experts in from all over the world to share their knowledge. That collaborative effort that Canex works hard to portray is what helps drive this industry forward. Cannabis is global and we need to come together and talk. Canex provides us with that platform!” stated Dr. Annabelle Manalo-Morgan.

“CanEx offers an unparalleled opportunity for aspiring entrepreneurs, investors, policymakers, and advocates to shape the future of cannabis legalization in the Caribbean and beyond. Anyone looking to advance the growing cannabis movement in the region and worldwide should attend to learn, connect, and grow.” stated President and CEO of the Marijuana Policy Project Toi Hutchinson.

“The incredible quality of both education and experience. You’ll have outstanding content, fun downtime events where the networking magic happens, The Who’s Who of the industry to network with, and all set in a beautiful location that has a burgeoning cannabis market which makes the intensive work of participating wholeheartedly in a conference both more enjoyable and also incredibly productive. When you invest precious resources (ie time and money) to attend an event like CanEx, getting so much out of these four days is awesome!” stated President and CEO of Bhang Inc. Jamie L Pearson.

“It gives me great pleasure to bring the world to Jamaica to hear about the cannabis industry, the potential for wealth, and the potential Job creation. It gives me great pleasure to invite the mostly white legal industry to a Black country. I believe Canex Jamaica is an amazing intersection of how large the industry can become, and the exploration and education of the
culture of ganja.” stated Founder and CEO of Simply Pure Wanda James.

A limited number of tickets to CanEx Jamaica are still available. Find out more at: canexjamaica.com

Study Associates Cannabis Use With Lower BMI Among Those With HIV/HCV

As of 2020, it was estimated that roughly 38.4 million people around the world have HIV. HIV is a very serious health condition that causes AIDS and interferes with the body’s ability to fight against infections.

It is estimated that roughly 58 million people around the globe have hepatitis C. Hepatitis C is a viral infection that can cause the liver to become inflamed, and if not properly treated, hepatitis C can lead to serious liver damage in suffering patients.

Many people that are diagnosed with either HIV or HCV also suffer from the other condition as well. As with virtually every health condition, having a healthy body mass index (BMI) is important. A recent study in France found that medical cannabis use was associated with a lower BMI in patients diagnosed with HIV and HCV. Below is more information about it via a news release from NORML:

Marseille, France: People co-infected with HIV and hepatitis C who consume cannabis are at a lower risk of being overweight, according to data published in the journal AIDS Education and Prevention.

French investigators assessed the relationship between cannabis use and body mass index (BMI) in a cohort of 992 HIV/HCV patients. Consistent with prior research, they reported that a history of marijuana use was “inversely associated with BMI.”

Prior studies involving HIV/HCV subjects have also identified a link between cannabis use and a lower risk of diabetesfatty liver disease, and early mortality.

Other case control studies have consistently reported that those with a history of marijuana use are less likely than abstainers to be obese or to suffer from type 2 diabetes.

Full text of the study, “Cannabis use as a protective factor against overweight in HIV-hepatitis C virus co-infected people,” appears in AIDS Education and Prevention. Additional information on cannabis and HIV/AIDS is available from NORML.

Study Finds That CBD Oil Mitigates Chemotherapy-Induced Neuropathy

I have said it before and I will say it again – cancer is one of the worst things on earth. If you or a loved one has ever battled cancer, then you know firsthand how awful cancer can be. Unfortunately, it’s something that millions of people die from every year, with millions more being diagnosed during the same duration of time.

The World Health Organization estimates that in 2020 alone, over 10 million people died from cancer around the world, with cancer being to blame for one out of every six deaths on earth.

Various treatments are currently incorporated into strategies to battle cancer, with one of the most common forms of treatment being chemotherapy. Chemotherapy is a drug treatment involving powerful chemicals that aim to kill fast-growing cells in the human body.

Chemotherapy can be effective in some cases, but it yields numerous side effects to some degree in all cases. One common side effect is neuropathy. Chemotherapy can damage the nervous system around the brain and spinal cord.

Fortunately for chemotherapy patients that must undergo the treatment, cannabidiol appears to help mitigate chemotherapy-induced neuropathy according to a recent study out of Denmark. Below is more information about it via a news release from NORML:

Roskilde, Denmark: The short-term administration of CBD oil extracts is safe and effective in patients suffering from chemotherapy-induced peripheral neuropathy (CIPN), according to data published in the journal Supportive Care in Cancer.

Danish investigators assessed the twice daily administration of CBD oil (300 mg/daily) in patients receiving either oxaliplatin or paclitaxel-based chemotherapy. Subjects used CBD for a period of eight days immediately following their first cycle of chemotherapy. Patients outcomes were compared to those of similarly matched controls.

Researchers reported that the use of CBD was associated with pronounced improvements in patients’ pain-related outcomes, including cold sensitivity and throat discomfort.

“CBD attenuated early symptoms of CIPN with no major safety concerns,” they concluded. “Long-term follow-up is ongoing. Results should be confirmed in a larger, randomized study.”

Separate studies have identified an association between patients’ long-term use of cannabis products and statistical improvements in cancer-related symptoms as well as significant reductions in their use of prescription painkillers.

Full text of the study, “Oral cannabidiol for prevention of acute and transient chemotherapy-induced peripheral neuropathy,” appears in Supportive Care in Cancer.

Study Finds Cannabis Extract Effective For Refractory Chronic Pain Patients

The most common health condition that people use cannabis to treat is pain. Patients can experience pain for any number of reasons, and to varying degrees of severity. For some patients the pain is only temporary, and medical cannabis helps during flare ups.

For others, pain can be so common in their lives that the pain becomes chronic, and in the worst cases, the pain can prove to be completely debilitating and not able to be treated by pharmaceutical medications (refractory chronic pain).

Pharmaceutical medications geared towards treating pain, even when they work, are often extremely addictive and the use of them can cause major health issues, including death. Cannabinoids alone, on the other hand, have never killed anyone in recorded human history, and in the cases of some patients with refractory chronic pain, the use of medical cannabis is very effective.

That was demonstrated in a recent study focusing on medical cannabis and refractory chronic pain out of Australia. Below is more information about it via a news release from NORML:

Sydney, Australia: The administration of cannabis extracts containing equal quantities of THC and CBD is associated with reduced pain intensity and improved sleep in patients with chronic refractory pain conditions, according to data published in the journal Medical Cannabis and Cannabinoids.

Australian investigators assessed the safety and efficacy of whole-plant cannabis oil in a cohort of 151 chronic pain patients. Participants in the trial used the extract daily for at least three months. All of the subjects in the trial suffered from conditions that were unresponsive to conventional analgesics, such as opioids and NSAIDs (non-steroidal anti-inflammatory drugs). Trial subjects were most likely to be diagnosed with neuropathy, musculoskeletal pain, or arthritis.

Researchers reported, “Pain impact scores were significantly reduced across the cohort. Additionally, most subjects reported improvements in sleep disturbances and fatigue.” The majority of side-effects reported by patients were categorized as mild; these most frequently included sleepiness, dizziness, and dry-mouth.

They concluded: “This analysis presents real-world data collected as part of standard of care. … The results of this study demonstrated a significantly positive effect of [a proprietary formulation of] oral medicinal cannabis oil on the impact of pain. … Amelioration of the impact of pain confirms continued prescribing of this formulation and validates our observational methodology as a tool to determine the therapeutic potency of medicinal cannabinoids.”

Survey data estimate that nearly one-third of patients suffering from chronic pain conditions acknowledge using cannabis products. Among patients in US states where medical cannabis access is permitted, over 60 percent are qualified to use it to treat pain.

Full text of the study, “Medical cannabis for the treatment of chronic refractory pain: An investigation of the adverse event profile and health-related quality of life impact of an oral formulation,” appears in Medical Cannabis and Cannabinoids. Additional information about marijuana for pain is available from NORML.