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Researchers In Israel: Cancer Patients “Improved Significantly” After Medical Cannabis Use

Cancer is absolutely one of the worst things on this planet. If you or a loved one has suffered from cancer then you know firsthand how awful it is.

Scientists and doctors have worked countless hours over many decades to try to get to the bottom of what causes cancer in an attempt to try to prevent it, as well as working to determine what treatments are effective for people that develop cancer.

The cannabis plant is often the subject of cancer treatment research, with quite a bit of research determining that cannabis seems to be beneficial to some extent. That is what researchers in Israel seemed to find when they recently conducted a medical cannabis study involving oncology patients.

“The use of medical cannabis (MC) to treat cancer-related symptoms is rising. However, there is a lack of long-term trials to assess the benefits and safety of MC treatment in this population. In this work, we followed up prospectively and longitudinally on the effectiveness and safety of MC treatment.” the researchers stated.

“Oncology patients reported on multiple symptoms before and after MC treatment initiation at one-, three-, and 6-month follow-ups. Oncologists reported on the patients’ disease characteristics. Intention-to-treat models were used to assess changes in outcomes from baseline. MC treatment was initiated by 324 patients and 212, 158 and 126 reported at follow-ups.” the researchers stated regarding the study’s methodology.

“Most outcome measures improved significantly during MC treatment for most patients (p < 0.005). Specifically, at 6 months, total cancer symptoms burden declined from baseline by a median of 18%, from 122 (82-157) at baseline to 89 (45-138) at endpoint (−18.98; 95%CI= −26.95 to −11.00; p < 0.001). Reported adverse effects were common but mostly non-serious and remained stable during MC treatment.” the researchers determined.

“The results of this study suggest that MC treatment is generally safe for oncology patients and can potentially reduce the burden of associated symptoms with no serious MC-related adverse effects.” the researchers concluded.

Feel free to share the results of this study with people that you know. As always, make sure to consult with your doctor before starting any medical treatment, including medical cannabis treatment.

Are More Potent Cannabis Strains On The Way?

Israeli researchers are able to increase the levels of all kinds of cannabinoids by introducing a plant-based virus to the grow cycle

The boogie man of the modern legalization movement is the oft-repeated statement that what is available today is “not your grandparents’ weed.” Namely that modern strains are “more potent” than strains available in the 1960s and 1970s.

While this is certainly a hard claim to verify anecdotally since the modern cannabis industry has a much wider variety of cultivars as well as strain “strength,” genetically modified and engineered new strains were always going to be part of the mix.

However, there has been an interesting development in Israel, home of the world’s most cutting-edge research on cannabis. Researchers have now been able to successfully engineer and cultivate a plant with up to 17% higher THC and 25% higher CBG levels, plus 30% more terpenes.

Further, for the first time, it appears possible to tailor individual strains plus the ratio between them. The method that the researchers used influences the production of active substances in the growing plant. They developed an innovative technology that allows a specially engineered virus to “infect” the plant to create the chemical reactions that produced custom levels of desired cannabinoids in their research crops.

The medical impact alone is significant. Not to mention a much more efficient use of space – which is even more significant when cultivating inside. However, this is research that won’t stay inside either a lab or even corporate cultivation for long. Home growers will be able to use this technology too.

Custom cultivated cannabis seems just around the corner.

Out of the Lab and Influencing the Industry?

One of the other really interesting aspects of this development is its potential impact on “whole-plant” medicine. In the world of pharma, individual compounds (like THC or CBD isolates) have been a major focus of the formal pharma part of the industry – and for several reasons.

The first is the stability of strains themselves. Growing cannabis with consistent levels of any cannabinoid is not easy to do on a corporate scale (as many commercial growers, even with pharmaceutical plant experience have discovered). Using this innovative technology would certainly help increase the stability of crops, no matter what kind of seeds were used.

Beyond this, the impact of highly personalized medicine, created not by a large company but by start-ups and even individuals, is the cusp of a revolution most in the industry hoped they would see sooner rather than later.

The other side of this kind of technological development is that in some ways it is a direct threat to biodiversity – which is also a huge industry issue.

The future most certainly, is “here.”

Attend Cannabis Europa In London June 28-29th

The emerging legal cannabis industry in Europe is at a critical juncture. After Malta became the first country to pass a national, no THC-limit adult-use legalization measure late last year several countries in the region are expected to follow in the near future.

Medical cannabis reform continues to spread across Europe, and with it, the expansion of the continent’s medical cannabis industry. The rise of adult-use legalization will obviously impact Europe’s medical cannabis industry, however, it’s still largely unknown to what extent that will be and how both sectors of the industry will operate alongside each other.

What is known is that the rest of this decade will no doubt prove to be the biggest decade in history when it comes to Europe’s emerging cannabis industry. The policies, rules, regulations, and other industry framework components that are created and implemented this decade will largely determine what the future of Europe’s cannabis industry looks like for decades to follow.

With that in mind, it’s more vital than ever for cannabis entrepreneurs, policymakers, and other leaders to network and learn from each other as much as possible. An amazing opportunity to do exactly that is coming to London on June 28-29, 2022 when Cannabis Europa’s flagship event comes to Old Billingsgate.

“We are ultimately trying to change society by bringing about acceptance and accessibility to cannabis in Europe.” stated Stephen Murphy, Co-Founder and CEO of Prohibition Partners at last year’s Cannabis Europe event. It’s a mission that remains true for this year’s event as well.

The venue for the event, Old Billingsgate, encompasses three versatile spaces and a beautiful terrace with unrivaled views of Tower Bridge, City Hall, The Shard, and London Bridge. The event’s two-day agenda covers a range of topics. Below is a sampling of the event’s speakers. For a full list click on this link:

  • Benedikt Sons – Co-founder, managing director, and CEO of Cansativa Group
  • Kristine Lütke MdB – Member of the Free Democratic Party
  • Dr Carl Hart – Professor of Psychology at Columbia University
  • CJ Wallace – Founder of Think Big
  • Hannah – Co-Founder and Non-Executive Director of Medcan Support
  • Dr Kojo Koram – Lecturer in Law at Birkbeck School of Law, University of London

The Cannabis Europa event taking place in London later this month will also include an expo floor featuring dozens of cannabis companies. The expo floor is a great way to network with exhibitors and attendees, as well as to learn about the latest products and services in the cannabis space.

Cannabis Europa will also offer a digital networking platform that will enhance the conference experience and help attendees get the most out of the two-day event. Features include viewing the attendee list, exploring partners’ virtual exhibition booths, learning and conversing via virtual ‘discussion rooms’, and much more. You can find more information about Cannabis Europa, including how to register for the event, at: www.cannabis-europa.com

Researchers Find CBD To Be An Effective Form Of Oral Care Treatment

Having a wound in your mouth can be very uncomfortable, and in some cases, can lead to serious health issues. Developing a wound in your mouth can happen due to a number of factors, and regardless of the reason, it’s something that needs to be taken seriously.

Failing to properly care for a mouth wound can lead to infections in some cases, and at the very least, it will make the problem last longer if it goes untreated.

Researchers in Thailand recently examined the ability of cannabidiol (CBD) to treat oral inflammation, gingival wounds, and ulcers by using a scratch test assay and evaluating cytotoxicity.

“The hemp extract and CBD significantly decreased TNF-α release by up to 91.05 ± 2.91% and 50.78 ± 7.21% of LPS activity, respectively, in a dose-dependent manner, compared to 10 µg/mL hydrocortisone (61.67 ± 3.79%). The hemp extract and CBD also significantly decreased IL-1β release, also in dose-dependent response, up to 78.03 ± 3.34% and 85.87 ± 1.11% of LPS activity, respectively, compared to 5 µg/mL hydrocortisone (80.81 ± 3.55%).” the researchers stated.

“The mean percentage of closure of the wound area was 27.92 ± 1.21% when exposed to 5 µg/mL hemp extract and 33.49 ± 1.67% when exposed to 0.5 µg/mL CBD, compared to 24.34 ± 2.29% for non-treated control.” the researchers went on to say.

“Our study demonstrates that both hemp extract and CBD can inhibit TNF-α and IL-1β production in LPS-induced RAW 264.7 cells and promote wound healing in HGF-1 cells. This is the first to show that short-term exposure to hemp extract and CBD promoted gingival fibroblast wound healing, demonstrating that hemp extract and CBD have potential benefits in the treatment of oral inflammation and ulcers.” the researchers concluded.

If you are experiencing any of the conditions mentioned in this article make sure to contact a medical professional as soon as possible before trying any new treatments.

Attend The Cannabis Normal! Conference In Berlin Next Month

Germany will never become the first country to legalize cannabis for adult use. That designation will forever go to Uruguay. However, legalization in Germany will ultimately prove to be the biggest cannabis prohibition domino to fall when historians look back on the global cannabis reform movement years from now.

Legalization in Germany is going to usher in a new era for cannabis in Europe and the rest of the planet. Germany’s economy is larger than any other economy on earth with the exception of the United States, China, and Japan. The United States is not nearly as close as Germany when it comes to implementing legalization, and China and Japan remain two of the worst places on earth for cannabis policy.

With news recently surfacing that adult-use legalization will be sped up in Germany according to the nation’s Health Minister, and potential budgetary ramifications if that doesn’t happen, reform is closer than ever. When legalization inevitably happens in Germany, it will be truly historic and will speed up reform efforts everywhere else around the globe.

It is extremely important for cannabis advocates and members of the industry to recognize the efforts of those that have helped bring cannabis reform efforts to this point in Germany, and no organization deserves more recognition than the German Cannabis Association.

The German Cannabis Association (DHV) is a professional cannabis advocacy group led by private legalization activists. Their tireless efforts over the course of many years have made a tremendous impact in Germany and have directly contributed to Germany’s current reform momentum.

DHV was originally founded in May 2002, and per its website, DHV “does not serve personal enrichment, but to make progress in hemp politics.” As DHV also points out on its website, it serves as “a counterbalance to corporate interests and fundamentally opposing forces, such as the police unions.” The DHV team does outstanding work, is extremely knowledgeable, and they are on the frontlines of cannabis reform efforts in Germany on a daily basis.

The German Cannabis Association (DHV) is organizing the third edition of the Cannabis Normal! Conference from June 17th to 19th, 2022 in the Alte Münze in Berlin. The conference’s program will largely involve exploring and discussing the intimate details of the upcoming cannabis legalization measure that is expected to be unveiled in Germany as early as this summer.

In addition to discussing the nuanced details of cannabis policy reform in Germany, hemp will also be a major topic at the event with discussions led by well-known guests from science and politics including drug policy spokesman Carmen Wegge (SPD), Dr. Kirsten Kappert-Gonther (Greens), Kristina Lütke (FDP) and Ates Gürpinar (Left).

It is vital that consumers have a voice in the legalization process in Germany, and fortunately, DHV has developed eleven sessions to cover every important facet of what Germany’s cannabis legalization model should include. It’s a great way to get educated about German legalization efforts and what to expect in the coming months. The information presented will be extremely timely, with upcoming hearings in the Bundestag expected to begin in the near future.

Below are sessions taking place at the upcoming Cannabis Normal! Conference:

More information about the schedule and program of the Cannabis Normal! Go to: cannabisnormal.de

For press inquiries and accreditations please contact Simon.Kraushaar@hanfverband.de

Topical CBD Ointment Efficacious For Psoriasis According To Thailand Researchers

Psoriasis is a skin condition that involves the development of a rash with itchy, scaly patches. The most common locations on the human body where psoriasis develops are the knees, elbows, butt, and scalp.

Unfortunately, it is still largely unknown what causes psoriasis. The current theory behind the cause seems to involve a combination of genetics and environmental issues, however, researchers are still trying to get to the bottom of it.

It is estimated that as much as two to three percent of the world’s population suffers from the condition. Fortunately, researchers in Thailand recently determined that CBD ointment may be an effective treatment for psoriasis. Below is more information about it via a NORML news release:

Bangkok, Thailand: The topical application of an ointment containing 2.5 percent CBD improves symptoms of psoriasis, according to the findings of a randomized, placebo-controlled study published in the Journal of the European Academy of Dermatology and Venerology.

A team of investigators affiliated with King Chulalongkorn University Hospital and Thammasat University Hospital in Thailand assessed the twice daily application of either CBD or placebo over a 12-week period in 51 patients with mild plaque-type psoriasis.

Areas treated with CBD showed significant improvements compared to areas treated with the placebo. Researchers did not identify any adverse effects attributable to the use of CBD.

“Our results indicated a trend of favorable response in the treatment with CBD, which has emerged as a therapeutic option for psoriasis,” authors concluded. “These outcomes will pave the way for future studies on [the] therapeutic effects of CBD.”

Prior studies have previously shown that CBD may reduce certain types of skin inflammation, including erythemapruritis, and acne.

Full text of the study, “Topical cannabidiol-based treatment for psoriasis: A dual-centered randomized, placebo-controlled study,” appears in theJournal of the European Academy of Dermatology and Venerology.

CBD Hemp Business Fair Is Coming To Spain

Cannabidiol (CBD) currently has the designation of being the most popular cannabinoid on earth. As proof of that claim, consider the fact that CBD is searched more often on Google than any other cannabinoid, including tetrahydrocannabinol (THC), and that’s been the case since December 2016.

In addition to being queried more often on the world’s most popular online search engine than its cannabinoid counterparts, hemp-derived CBD is legal in far more regions of the planet compared to THC. It is estimated that the global CBD market was worth nearly 5 billion USD in 2021 and that it could be worth as much as 47 billion USD by 2028. That figure doesn’t include the global market for industrial hemp, which is set to experience a 33%+ compounded annual growth rate through 2030 according to at least one estimate.

You will be hardpressed to find an industry that is already worth billions of dollars and yet is still set to experience the level of exponential growth that the global CBD and industrial hemp industry will experience in the coming years. There is literally no better time to get into the CBD industry than right now, and a great way to do exactly that is to attend the upcoming CBD Hemp Business Fair in Barcelona on October 7-9, 2022.

Spannabis, the world’s largest cannabis trade show with more than 20 years of experience, is launching this amazing new event focused on CBD and industrial hemp. The fair is expected to have more than 100 brands present on a 12,000 square meter expo floor. Over 1,500 industry professionals and 15,000 visitors are expected to be in attendance over the course of the 3-day event.

CBD Hemp Business Fair will feature an event networking app that helps facilitate collaborations between exhibitors and event attendees before and during the event. The app is a very useful tool to promote companies, make appointments, and discover new potential clients.

The event’s showroom will feature demonstrations, presentations, and entertainment including cooking demonstrations and live music. The event will also include an outdoor food truck area, the CBD Champions Cup, and the CBD and Hemp Awards. If you want to get into the emerging CBD and hemp industry, or just want to learn more about its products and services, you do not want to miss this event!

Brazilian Researchers Determine That CBD Is Safe For Dogs

An area of the emerging cannabis industry that is often overlooked is cannabis products for pets. Worldwide, it is estimated that over half of the households around the globe own a pet and many of those households own more than one pet.

The most popular pet type around the world is dogs, with as many as 33% of households around the planet estimated to own at least one dog. With that in mind, any product that can effectively and safely help dogs live better lives is obviously something that there would be a tremendous demand for.

Medical cannabis products for pets is still a very young sector within the emerging cannabis industry, and quite a bit of research is needed to help ensure product safety.

However, at the macro level, cannabis appears to be safe for pets, especially cannabidiol, as long as it’s administered in the right dosage level. Below is more information about it via an abstract of a recent study conducted in Brazil:

The review was systematically performed in Medline (via Pubmed®) and Latin American and Caribbean Health Sciences Literature (LILACS) databases, with period restriction (between 1990 and 2021). The qualified articles (n=19), which met the previously established inclusion criteria, were critically evaluated.

Based on the literature review, it is possible to infer safety in the administration of cannabis-based products for the treatment of dogs, especially products rich in cannabidiol (CBD), free or with low concentrations of tetrahydrocannabinol, under the conditions evaluated. In addition, CBD products potentially promote improved quality of life and reduce pain perception in animals affected by canine osteoarthritis.

Finally, owing to the lack of large-scale and robust clinical research studies, the performance of clinical trials, considering the individual characteristics of each cannabis-based product (composition, concentration, nature of adjuvants, dosage form, route of administration), is strongly encouraged.

Now, before you run out and grab the nearest cannabis product that you can find and try to give it to your dog, keep the results of this study in context.

Dogs are far more sensitive to medications than humans, and not only is it important to get the right medical cannabis product designed specifically for a dog of a specific size, it is also important to use the right dosage level and use the right consumption method.

Check with a veterinarian prior to administering medical cannabis products to your dog or any other pet that you may have.

Medical Cannabis Associated With Sustained Improvements In Anxiety And Depression

Anxiety and depression are two of the most common mental health conditions that patients suffer from globally. As many as 275 million people suffer from anxiety worldwide, and roughly the same number of people suffer from depression around the world.

For many patients, anxiety and depression go hand in hand, and suffering from the conditions can be debilitating and negatively impact nearly every aspect of daily life.

Fortunately, the cannabis plant may be able to help treat both conditions, as described in a recent news release from NORML:

Calgary, Canada: Patients with symptoms of anxiety and/or depression report sustained improvements following the use of cannabis, according to survey data published in the journal Psychiatry Research.

Canadian investigators surveyed over 7,000 patients authorized to access medical cannabis products. The average age of subjects in the study was 50 years old. All of the study’s subjects belonged to a licensed Canadian medical cannabis clinic.

Authors reported “statistically significant improvements” between subjects’ baseline and follow up scores on validated measurements of anxiety and depression. Symptom improvements were sustained for at least one year.

“To our knowledge, this study is the largest completed to date examining the impact of medical cannabis use on anxiety and depression outcomes utilizing longitudinal data and validated questionnaires,” they concluded. “It provides evidence on the effectiveness of medical cannabis as a treatment for anxiety and depression that otherwise is not currently available, demonstrating that patients who seek treatment with medical cannabis for anxiety and depression can experience clinically significant improvements. This study offers reasonable justification for the completion of large clinical trials to further the understanding of medical cannabis as a treatment for anxiety and depression.”

Full text of the study, “Medical cannabis use in Canada and its impact on anxiety and depression: A retrospective study,” appears in Psychiatric Research.