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Research Finds That Nanoformulated CBD Is Effective For Skin Conditions

Skin conditions, such as acne, psoriasis, and eczema, affect millions of people worldwide. International researchers estimate that over 125 million people suffer from just eczema alone, with roughly 30% of those eczema sufferers eventually developing psoriatic arthritis.

A team of researchers affiliated with various academic universities in India and Australia recently examined the efficacy of nanoformulated cannabidiol as a treatment for serious skin conditions and wound care. Their findings were published in the European Journal of Pharmaceutics and Biopharmaceutics.

“Cannabidiol (CBD), a non-psychoactive chemical derived from Cannabis sativa L., has significant dermatological potential due to its antinflammatory, antioxidant, and wound healing attributes.” the researchers wrote. “However, its clinical usage is limited by instability, minimal skin penetration, and poor solubility.”

“Nanotechnology-based delivery systems such as pickering emulsions, cryogels, lipid nanoparticles, and nanomicelles have emerged as promising strategies to enhance localized skin delivery, improve penetration, enable sustained release, and reduce adverse effects.” they also wrote.

“According to this analysis of 16 papers and 18 patents (2019-2024), CBD that has been nanoformulated offers improved tolerability, sustained release, and skin delivery. According to GRADE review, impacts on dermal absorption, inflammation, and wound healing demonstrated intermediate certainty, but outcomes such as skin penetration, controlled release, and safety showed high certainty.” the researchers found.

“Applications for acne, psoriasis, and eczema show enhanced patient compliance and efficacy. Despite clinical and regulatory obstacles, nano-CBD platforms provide a safe, focused, and efficient approach to improving dermatological care.” the researchers concluded.

A recent market analysis by The Business Research Company estimated that the global cannabis cosmetics market will grow “from $5.48 billion in 2024 to a projected total of $7.29 billion in 2025 at an impressive compound annual growth rate CAGR of 32.8%.”

Himachal Pradesh Cabinet Approves Hemp Pilot

The government in Himachal Pradesh, a state in India, has approved a pilot study to examine the potential benefits of permitting industrial hemp cultivation and the creation of related medical products and scientific research.

“The Himachal Pradesh cabinet has approved the report of a committee recommending the controlled cultivation of cannabis for industrial, scientific, and medicinal purposes, setting the stage for its legalisation in the state. The report, previously passed by the Himachal Vidhan Sabha, was prepared with inputs from opposition BJP members, horticulture experts, and scientists.” Indian Express stated in its local coverage.

“Controlled cannabis cultivation will be undertaken jointly by two agricultural universities—Chaudhary Sarwan Kumar Krishi Vishvavidyalaya, Palampur, and Dr YS Parmar University of Horticulture, Nauni, Solan. The Agriculture Department has been designated as the nodal body for the initiative.” the outlet also reported.

A recent market analysis by Knowledge Sourcing Intelligence estimates that the global industrial hemp market “is forecasted to grow at a CAGR of 17.75% between US$9.913 billion in 2025 to US$22.438 billion in 2030.”

A separate market analysis recently published by Markets and Markets predicts an even larger global industrial hemp market in the future, estimating that “the industrial hemp market is estimated at USD 11.03 billion in 2024 and is projected to reach USD 30.24 billion by 2029, at a CAGR of 22.4% from 2024 to 2029.”

The booming industrial hemp market is not limited to just industrial applications and medical products. According to analysts at Maximize Market Research, “the global hemp-infused beverage market is experiencing significant expansion, driven by increasing consumer awareness of hemp’s health benefits and a growing demand for functional, wellness-oriented drinks.”

“In 2023, the market was valued at USD 3.63 billion and is projected to grow at a compound annual growth rate (CAGR) of 28.9% from 2024 to 2030.” the analysts predict.

Textile Industry Members In India And South Korea Forge Hemp Partnerships

At a recent meeting hosted by the Wool and Woolens Export Promotion Council, members of the textile industries in both India and South Korea announced plans to, among other things, forge partnerships to tap into the industry potential of the industrial hemp fiber sector.

“Attendees discussed innovative ways to greater integrate hemp into India’s textile ecosystem, and the benefits of blending hemp with wool to create sustainable products that can help meet the rising global demand for eco-friendly materials.” reported Hemp Today in its original coverage.

“Also during the meeting, India’s Minister of Textiles, Giriraj Singh, reaffirmed his commitment to fostering the growth of commercial hemp production, pledging to collaborate with Uttarakhand Chief Minister Pushkar Dhami to draft a proposal aimed at aligning policies and promoting growth within the sector.” the outlet also reported.

Despite a long history with the hemp plant, India does not currently have national hemp industry regulations permitting such activity. However, some local jurisdictions have adopted industry rules and regulations, and India’s hemp industry should experience continued growth in the foreseeable future.

According to a recent market analysis by Technavio, “the global industrial hemp market size is estimated to grow by USD 13.90 Billion from 2024 to 2028,” and “the market is estimated to grow at a CAGR of over 25.25% during the forecast period.”

In other news out of India, senior state police officials in India recently told Al Jazeera that they have “seized about 600 tonnes of cannabis in the three years until 2023, goods worth $200m, and have also arrested 8,500 drug traffickers.”

“The police have also destroyed about 28,000 hectares (70,000 acres) of cannabis plantations in Odisha between 2021 and 2023, the highest for cannabis in the country, JN Pankaj, a former inspector general of the Special Task Force of the Odisha Police, told Al Jazeera.” the media outlet also reported.

Clinical Trial In India Finds Oral CBD Is Safe And Effective At Treating Anxiety

International health investigators estimate that about 4% of the world’s human population suffers from some form of anxiety, although, researchers do not know the exact number. Anxiety often goes undiagnosed for various reasons in certain parts of the world so the actual rate may be higher than reported.

Anxiety is often described as involving intense, excessive, and persistent worry and fear about everyday situations. Physical symptoms of anxiety can include a fast heart rate, rapid breathing, sweating, and/or fatigue.

Many of the pharmaceutical treatments that are commonly prescribed to anxiety patients involve a long list of possible side effects. Some cases of anxiety are so bad that pharmaceutical treatments don’t even work.

Fortunately, orally administered cannabidiol (CBD) products may be able to help in some cases according to a recent clinical trial conducted in India. Below is more information about the trial’s results via a news release from NORML:

Telangana, India: The administration of oral CBD is safe and effective for patients suffering from mild to moderate anxiety disorders, according to clinical trial data published in the Asian Journal of Psychiatry.

An international team of investigators assessed the efficacy of 150mg/mL of CBD versus a placebo in a cohort of 178 subjects with anxiety. Patients consumed either CBD or a placebo for 15 weeks.

Researchers reported, “The … CBD oral solution showed therapeutic efficacy, excellent safety, and tolerability in treating not only mild to moderate anxiety disorders, but also associated depression and disturbances in sleep quality with no incidences of withdrawal anxiety upon dose tapering and at the end of the treatment.”

They concluded: “In this Phase III study, … CBD oral solution exhibited superior efficacy in achieving the primary and secondary objectives when compared to the placebo group. … These results pave way for probable prospective use of … CBD … for various psychiatry disorders alone or in conjunction with other drugs.”

The findings are consistent with those of other clinical trials finding that CBD reduces levels of emotional exhaustionsocial anxiety disorder, and treatment-resistant anxiety disorders.

Full text of the study, “Evaluation of the efficacy, safety, and pharmacokinetics of nanodispersible cannabidiol oral solution (150 mg/mL) versus placebo in mild to moderate anxiety subjects: A double blind multicenter randomized clinical trial,” appears in the Asian Journal of Psychiatry.

Himachal Pradesh Inches Closer To Permitting Cannabis Cultivation

Himachal Pradesh is the northernmost state of India. Host to the Dalai Lama, it is known for its scenic towns and resorts and is the second largest producer of apples in India only behind Kashmir. Soon, farmers will likely get the chance to cultivate a new crop – cannabis hemp.

India’s Narcotic Drugs and Psychotropic Substances Act, 1985 prohibits cannabis. However, individual states in India have set their own cannabis policies in some cases, and lawmakers in Himachal Pradesh are in the process of legalizing hemp production. Hemp cannabis, from a legal standpoint, is distinguished from what is considered to be non-hemp cannabis by a THC-content threshold.

The THC threshold for what constitutes hemp and what does not varies around the world, typically within the range of .2-1%. Comparatively, THC in cannabis products widely sold in countries like Uruguay, Canada, and the United States ranges from 15-30%+.

Still, what is being pursued in India is still significant for local farmers who are looking to cultivate a new crop. Per excerpts from The Hindu:

A committee comprising lawmakers that explored the possibility of legal cultivation of cannabis has recently recommended cultivation of ‘non-narcotic use of cannabis for medicinal, industrial, and scientific use’.

An approval from the State Cabinet is awaited after which a policy is expected to be framed soon by the State government on cannabis cultivation keeping in view the provisions of NDPS Act, 1985, and NDPS Rules, 1989.

Unfortunately, the previously cited article dedicates a considerable amount of time to discussing unfounded ‘concerns’ about the reform being pursued. What lawmakers are pursuing is the legalization of low-THC, high-CBD industrial hemp, sometimes referred to as ‘floral hemp’ or ‘cannabis light.’

Numerous peer-reviewed studies on our website demonstrate that regulated CBD products are safe, and a study we published earlier this month found that inhaled floral hemp doesn’t negatively impact driving performance. It’s a largely benign substance that people should not be concerned about and that the farmers of Himachal Pradesh should absolutely be permitted to cultivate.

India Is Working To Legalize Industrial Medical Cannabis Cultivation

India has one of the oldest connections to cannabis out of any nation on earth, particularly for sacramental purposes. According to Psychology Today, “The earliest mention of cannabis has been found in The Vedas, or sacred Hindu texts. These writings may have been compiled as early as 2000 to 1400 B.C.”

A common form of cannabis in India is bhang, which is a drink infused with various levels and types of cannabis. Bhang is reportedly common in many parts of India, even though it is technically illegal.

According to section 20 of India’s Narcotic Drugs and Psychotropic Substances Act (1985), ‘the sale/purchase, transportation, interstate import/export or any other commercial activity of cannabis’ is a punishable offense.

Cannabis use is largely tolerated in India, although there are definitely instances of people receiving harsh punishments for simple possession. Medical cannabis use is legal to some degree, with the Centre telling the Delhi High Court in January 2022 that the use of cannabis is ‘not completely banned’ and that ‘medical and scientific use of cannabis is allowed under the law.’

Uttarakhand became the first state in India to allow commercial cultivation of hemp crops back in 2018, and in 2019 the Madhya Pradesh government followed suit. In February 2020 India permitted its first medical cannabis clinic to open in Bengaluru.

Yet, large-scale cultivation of medical cannabis nationwide has remained out of reach. That could be changing soon. Per The Tribune:

Chief Parliamentary Secretary (CPS) Sunder Singh Thakur said today that the state government was working to legalise the cultivation of cannabis for medicinal and industrial purposes. The government would formulate a policy for cannabis cultivation so that farmers could get additional income, he added.

He presided over the inaugural ceremony of the three-day training workshop of the Himalayan Forest Research Institute (HFRI), Shimla, at the Atal Bihari Vajpayee Institute of Mountaineering and Allied Sports, Manali.

How long it will take for such reforms to be fully implemented is unclear at this time. What is clear is that if India succeeds in its pursuits, it will move closer to taking its rightful spot as an international cannabis industry powerhouse.

Lawmaker In India: Promote Cannabis, Not Alcohol

Historically, cannabis was portrayed as ‘the scourge of man’ in film and by mainstream media. The related reefer madness-induced stigma was simultaneously perpetuated by lawmakers across the globe. Meanwhile, alcohol is embraced by most cultures and political majorities around the world and has been for a logn time, which is unfortunate given how much safer cannabis is compared to alcohol.

In fact, a team of international researchers once determined that cannabis is roughly 114 times safer than alcohol. Given that mathematical fact and the scientific research backing it up, why is cannabis illegal in so many places, and yet alcohol is permitted?

According to the World Health Organization, “The harmful use of alcohol is a causal factor in more than 200 disease and injury conditions,” and “Worldwide, 3 million deaths every year result from harmful use of alcohol. This represents 5.3% of all deaths.”

Conversely, no one has ever died in recorded human history from consuming cannabinoids alone. There have been examples of cannabis being contaminated and people dying from consuming the contaminants, but never from consuming the cannabinoids alone. Clearly, given those facts, cannabis prohibition policies are not based on science.

While it’s very important to highlight the hypocrisy of cannabis prohibition and simultaneous permitted alcohol consumption and sales, it’s also important to refrain from shaming people for alcohol use. Just as consuming cannabis is a personal choice, so too is the choice to consume alcohol. Prohibition of either substance doesn’t work.

With that being said, given the difference between the two from a safety standpoint, the more that people consume cannabis instead of alcohol is always a good thing, and something that governments should encourage as part of a harm reduction strategy.

That is a point that seems to be embraced by at least one lawmaker in India who is ramping up calls to regulate cannabis like alcohol. Per excerpts from Scroll.in:

A Bharatiya Janata Party MLA from Chhattisgarh has suggested the promotion of bhaang and cannabis as alternatives to liquor, claiming that those who consume the former rarely commit serious crimes, PTI reported on Monday.

While I don’t agree with some of the rhetorical alcohol shaming that is part of the conversation in India right now, I do agree with the sentiment on the pro-cannabis side to some degree.

Just as someone can consume alcohol responsibly and should be allowed to do so, so too should people be allowed to consume cannabis responsibly if that is their choice, and that should be true in India as well as everywhere else.