Tag: opioids

The opioid epidemic affects nearly every corner of the world. The War on Drugs is an absolute failure, make no mistake about that. However, opioid addiction is still a very serious issue and governments all over the planet are struggling to deal with the negative public health consequences of it.

This may sound obvious, but the best way to get people off of opioids, particularly unregulated opioids, is to get them to stop using them. Unfortunately, the approach by many governments has historically been incarceration, and that is not an effective way to deal with the problem as proven by no decline in usage rates throughout prohibition.

The cannabis plant has shown promise as a substitute for opioids, and a recent study in Canada found that self-reported unregulated opioid product users ‘frequently’ turn to cannabis to reduce their cravings. Below is more information about it via a news release from NORML:

Vancouver, Canada: Those who consume unregulated opioids frequently report using cannabis to mitigate their drug cravings, according to data published in the International Journal of Drug Policy.

Canadian investigators assessed cannabis use trends among a cohort of 205 consumers of non-prescription opioids. Many of the cohort were IV drug users and at-risk youth.

Nearly half of the study’s participants (45 percent) acknowledged using cannabis to manage opioid cravings. Of those, 62 percent “reported self-assessed decreases in opioid use during periods of cannabis use.” Subjects suffering from chronic pain were most likely to engage in opioid substitution.

Authors concluded: “In the present study, we observed that cannabis use to manage opioid cravings was significantly associated with self-assessed decreases in opioid use during periods of cannabis use among a structurally marginalized population of PWUD [people who use unregulated opioids]. The sub-analysis indicated that this association was mainly driven by those living with moderate to severe pain. … This suggests that future studies of cannabis substitution for opioid use should measure and analyze the impact of pain, as not doing so may lead to equivocal findings when the effects of cannabis substitution may vary based on the prevalence of chronic pain.”

Although numerous studies indicate that patients typically decrease their use of prescription opioids after initiating cannabis therapy, data regarding the relationship between cannabis use and non-prescription opioids is less consistent. According to a 2020 review paper: “Growing pre-clinical and clinical evidence appears to support the use of cannabis … to combat OUD [opioid use disorder]. The evidence summarized in this article demonstrates the potential cannabis has to ease opioid withdrawal symptoms, reduce opioid consumption, ameliorate opioid cravings, prevent opioid relapse, improve OUD treatment retention, and reduce overdose deaths. … The compelling nature of these data and the relative safety profile of cannabis warrant further exploration of cannabis as an adjunct or alternative treatment for OUD.”

Full text of the study, “Cannabis use to manage opioid cravings among people who use unregulated opioids during a drug toxicity crisis,” appears in the International Journal of Drug Policy. Additional information is available from the NORML Fact Sheet, ‘Relationship Between Marijuana and Opioids.’

It is estimated that roughly 1 out of every 5 people on earth suffers from chronic pain, with the likeliness of someone having the condition increasing with age. The rate of people over the age of 65 that suffer from chronic pain is as high as 85% according to at least one study.

Chronic pain is defined as being ongoing and lastly over 6 months, and can be caused by any number of factors. For some patients, chronic pain is a symptom of another condition, such as cancer. For others, its the result of an injury or accident.

Whatever the cause, chronic pain can be very tough to deal with. In some cases, it can be extremely debilitating and interfere with virtually every aspect of daily life. To make matters worse, when pain patients go to their doctor they are almost always met with one form of recommended treatment – opioids.

It is always worth mentioning that just because someone takes opioids, they shouldn’t be shamed for doing so. For some patients, it’s their only option, and for many other patients, it’s effective for their specific situation. Just as people shouldn’t be subjected to negative stigma for using cannabis, so too should they never be subjected to negative stigma for using opioids or any other medicine for that matter.

With that being said, cannabis is exponentially safer than opioids, and according to a new study many patients are reducing their reliance on opioids after starting medical cannabis treatment. Below is more information about it via a news release from NORML:

Milan, Italy: The long-term use of plant-derived cannabis extracts by patients with chronic pain is associated with reduced reliance on prescription opioids, according to data published in the European Review for Medical and Pharmacological Sciences.

A team of Italian researchers assessed the use of prescription opioids and other medicines in a cohort of chronic patients in the six months immediately prior to and immediately following their initiation of medical cannabis.

Authors reported that a significant percentage of subjects ceased their use of prescription opioids by the conclusion of the trial. They concluded, “Analyses by subgroups showed a statistically significant difference in the proportion of female opioid non-users before and after cannabis-based oil treatment (34.1 percent to 56.1 percent), as well as in the proportion of under-65 years old opioid non-users before and after cannabis-based oil treatment (32.5 percent to 55 percent), in the proportion of opioid non-users with non-severe comorbidity (33.3 percent to 54.2 percent), and … in the proportion of opioid non-users with a chronic pain condition (32.6 percent to 59.2 percent).”

The findings are consistent with dozens of other studies showing that pain patients typically reduce or eliminate their use of prescription opioids following the use of cannabis. Inconsistent with prior studies, authors did not identify an association between medical cannabis use and a significant reduction in patients’ use of other prescription drugs, including benzodiazepines.

Full text of the study, “Long-term cannabis-based oil therapy and pain medications prescribing patterns: An Italian observational study,” appears in European Review for Medical and Pharmacological Sciences. Additional information is available from the NORML fact sheet, ‘Relationship Between Marijuana and Opioids.’ Information on cannabis in the treatment of chronic pain is available from NORML.